The Paleozoic Era is marked by the rise of complex animal burrowing life about 539 million years ago. It also saw the rise of our ancestors, the synapsids, who came to dominate the era. Their reign, and the era itself, ended 252 million years ago with the end-Permian mass extinction, a volcanic cascade event that drove rapid global warming and widespread environmental collapse. In the Mesozoic Era that followed, mammals barely survived the age of dinosaurs.