A human baby born today, and a human baby born in 60,000 BCE have nearly indistinguishable DNA. There are differences but essentially humans are the same now as they were then. The popular website 23andme.com focuses on 23 changes in DNA that signify your ancestors recent migration. 23andMe.com, ancestry.com, and many others identify differences for their customers. Finally, the medical community is currently in an intense wave of identifying genetic differences that lead to medical problems with the idea of early diagnosis, prevention, and through the use of mRNA correction.
Through mtDNA sequencing, we currently believe the most recent common ancestor of all the Eurasian, American, Australian, Papua New Guinean, and African lineages dates to between 73,000 and 57,000 years ago.