Monodnaviria is a high-level biological realm of viruses characterized by a single-stranded DNA (ssDNA) genome. They are defined by their use of a specific protein (an HUH endonuclease) to initiate a process called rolling-circle replication.
Monodnaviria
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Monodnaviria
~1.75 Billion years ago (+/- 200 million)
single-stranded DNA viruses
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About 1.75 billion years ago, Monodnaviria evolved as “runaway” genetic loops (plasmids) that stole structural proteins from other viruses to become independent, single-stranded DNA parasites.
Subject: Virus Evolution.
By 1.75 billion years ago, the ancient double-stranded realms, Monodnaviria likely emerged from rolling-circle plasmids—circular DNA “apps” that escaped cellular control. By “hijacking” capsid genes from other viral groups, these modular entities transformed into infectious agents, populating the biosphere with resilient, compact viruses like Circoviruses and Nanoviruses.
Flashcard.
Which realm of viruses features single-stranded DNS and rolling-circle replication?.
Answer. Monodnaviria.
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