Monodnaviria is a high-level biological realm of viruses characterized by a single-stranded DNA (ssDNA) genome. They are defined by their use of a specific protein (an HUH endonuclease) to initiate a process called rolling-circle replication.
Monodnaviria
~1.75 Billion years ago (+/- 200 million)
single-stranded DNA viruses
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