Biological immortality, or negligible senescence, is not invincibility against accidents or violence, but rather the cessation of aging and the ability to prevent or cure all diseases, including genetic disorders. Essentially, it involves maintaining the body and its functions in a youthful state indefinitely. The key components of biological immortality include gene editing, disease cure and prevention, and aging process interruption.

I think we’ll attain biological immortality by about 2200 because rapid advancements in gene editing, disease treatment, cellular repair, and aging research, combined with the convergence of AI, biotech, and nanotech, will lead to a comprehensive understanding and control of human biology, enabling the cessation of aging and the prevention or cure of all diseases, including genetic disorders, thereby achieving negligible senescence and biological immortality.