Chimpanzees and bonobos are distinct species and cannot interbreed; no known hybrids exist despite their close physical resemblance. While their body structures, hands, and feet are similar, bonobos generally have a slimmer build, with longer legs relative to their arms and a more upright posture. Both are knuckle-walkers, but bonobos are noticeably more inclined to walk on two feet. Chimpanzee skin is often lighter at birth and darkens with age, while bonobos tend to have darker facial skin from birth and finer hair, giving them a softer appearance compared to the robust, muscular physique typical of chimpanzees.

Today, bonobos and chimpanzees showcase notable differences in their social structures and behaviors. Bonobos are known for their more egalitarian, matriarchal societies and frequent use of sexual behavior as a means of social bonding and tension reduction. In contrast, chimpanzees live in male-dominated hierarchies, with aggression often playing a larger role in social interactions, including territorial defense.